Industrial Microbiology

•Introduction to industrial microbiology: brief history, information on microrganisms, industrial and food fermentations,
•Microorganisms of industrial relevance: Retrieve the main microorganisms of industrial interest and their metabolic activities, techniques for their preservation: liquid, frozen, freeze-dried cultures.
•Traditional techniques of selection and improvement of micro-organisms of industrial interest: primary and secondary screening, mutagenesis, final selection.

● Microbial metabolites: Primary and secondary metabolites,

● Biotechnology of fermentations: Substrates for industrial fermentations, Use of biomasses and agro-food wastes and by-products as feed stocks for the production of microbial biomasses and "bio-based products"; Biorefineries, kinetics of production,

● Immobilization techniques: Procedures for passive immobilization Advantages and disadvantages of immobilization. Fermenters for immobilized microbial cells.

QUALITY MANAGEMENT AND PRODUCT PACKAGING

Introduction: Quality definition and scope, Quality planning, Quality tools, Quality in the design phase, Quality in the manufacturing phase, Quality in the procurement phase,

● Measurement assurance, Quality management systems, Six Sigma methodology.

● Cleaning and disinfection: CIP, COPs, disinfection systems in bioindustries.

● Prerequisite programs of HACCP (PRPs): GAP, GMP, GHP, GVP.

● Application of HACCP in bioindustries.

BFS 9203:Fermentation Technology Process

This course provides a comprehensive exploration of the core principles and applications of fermentation technology, focusing on the controlled use of microorganisms for industrial production. Students will learn the fundamental steps of upstream processing, including media formulation and sterilization, alongside the critical control of parameters like pH, temperature, and aeration during the fermentation itself. The course also covers downstream processing techniques for the efficient recovery, purification, and formulation of the desired biological products. Key aspects of bioreactor design, operation, and scale-up from laboratory to industrial scale are examined in detail. Ultimately, the course connects these technical processes to their real-world applications in producing pharmaceuticals, biofuels, food ingredients, and other valuable commodities.

 
 
 
 
 
 
 
 
 
 
 

BFS 9303:Advanced Research Methodology

Recovery and Purification of Biological Product

Industrial Bioreaction Engineering

Heat and mass transfer in bioreactor

BFS 9101:Advanced cell biology

The objective of this module is to provide a deep understanding of structure and function of prokaryotic, eukaryotic cells and Techniques in protein characterization (TIPC). Also account for methods of measurement to study proteomes and metabolomes including their advantages and disadvantages and applications. Lectures are devoted to studying the molecular functions of the different parts of the cell, cell-to cell organization, and current topics of cell biology. Different structure motifs of proteins. Multifunctional enzymes, membrane proteins, prediction of protein structures. Studies of physico-chemical properties of proteins and methodology for studies of these properties: Chemical characteristics of polypeptides, protein engineering, physical interactions determining the properties of proteins, role of hydrophobic interaction, conformation flexibility, protein stability, mechanisms of protein folding, interaction with other proteins, enzyme catalysis.